In the 1970s, young Gru tries to join a group of supervillains called the Vicious 6 after they oust their leader — the legendary fighter Wild Knuckles. When the interview turns disastrous, Gru and his Minions go on the run with the Vicious 6 hot on their tails. Luckily, he finds an unlikely source for guidance — Wild Knuckles himself — and soon discovers that even bad guys need a little help from their friends.